PEG-400: PEG-400is most suitable for soft capsules. Because PEG400 is liquid, it has wide compatibility with various solvents, is a good solvent and solubilizer, and is widely used in liquid preparations, such as oral liquids, eye drops, etc. PEG is the material of choice when vegetable oils are not suitable as active ingredient carriers. This is mainly because PEG is stable and not easy to deteriorate, and the injection containing PEG is very safe and stable when heated to 150 degrees Celsius. In addition, it can be mixed with high molecular weight (PEG) and its mixture has good solubility and good compatibility with drugs.
PEG-400, 600, 800: used as a base for medicine and cosmetics, as a lubricant and wetting agent in the rubber industry and textile industry. PEG-600 can be added to the electrolyte in the metal industry to enhance the grinding effect and enhance the luster of the metal surface.
Safety:
In the Food Additive Supplement Regulations of the Federal Food, Drug and Cosmetic Regulations, the use of Pharmacopoeia-grade polyethylene glycols for food chemicals has been approved for direct or indirect use as food additives. In 1985, FAO/WHO stipulated that the ADI value was 0-10mg/kg body weight Chemicalbook. GRAS (FDA, §172.820, 1985). Acute oral toxicity (mice) LD5033~35g/kg, intraperitoneal toxicity LD5010~13g/kg. Does not irritate the eyes, does not cause skin irritation and allergy.