Description
Chitosan is considered as one of the most promising biomaterials of the 21st century on accounts of its versatile nature, excellent biodegradability, biocompatibility, antimicrobial activity, non-toxicity and wide applications. Chitosan is derived from Chitin, a second most abundantly available natural polymer after cellulose.
Chitin is naturally found in the exoskeleton of shellfish such as crabs and shrimps, and in the cell membranes of fungi, yeasts, and other microorganisms. Chitin is not soluble in dilute acids, whereas chitosan is soluble in dilute acids.
Chitosan is primarily composed of glucosamine and N-acetyl glucosamine residues with a 1, 4-β-linkage. The presence of primary amines (-NH2) in chitosan gives it a net positive charge and is important for its biological properties.
Product Parameters
- Chitosan is derived from Chitin. It was the first polysaccharide identified by scientists, even before the discovery of cellulose
- Henri Braconnot isolated Chitin from mushrooms in 1811 for the first time
- The name of 'Chitin' is derived from the Greek word "Chiton" which means wrap.
- In 1859, Prof C. Rouget heated Chitin in presence of an alkaline medium for the first time and discovered 'Chitosan'
- The word 'Chitosan' was coined by Hoppe-Seyler in 1894
Uses
- Haemostatic action of chitosan is based on the rapid absorption of blood plasma that leads concentration of erythrocytes and platelet at injured place, followed by platelet activation and erythrocyte coagulation
- Chitosan promotes re epithelization by stimulating the proliferation of dermal fibroblast and inhibiting the proliferation of keratinocytes
- Chitosan act as an antimicrobial agent by causing the leakage of bacterial cell wall through charge-based interaction and inhibition of mRNA and protein synthesis at bacterial nuclei
- Analgesic effect of chitosan comes from the absorption of bradykinin and proton ions at inflammatory site followed by blocking of Arachidonic pathway by phospholipaseA2 inhibition
- Chitosan plays an important role for anti-inflammatory action by produce significant inhibition effect against inflammation mediator such as Interleukin (IL)- 2, IL-4, IL-6, IL-10 and IL-13, cytokines such as TNF-α, NF-kβ expression and AP-1 activation
- Chitosan protects the digestion of skin extracellular matrix by blocking the matrix metalloproteinase-2 expression
- Chitosan protects the skin from the exposure of UV radiation and act as a sun screening agent ( Sun protector factor around 0.89)
- Chitosan act as a cationic humectant that can easily absorbed to the negatively charged skin surface and hold the moisture content of skin. Moisture absorption capacity enhances with the increase of degree of deacetylation of chitosan
- Polycationic nature of chitosan helps to interact with polyanionic keratin that cause easy film formation around hair fibers. This film improves hair strength ,hair softness, and avoid hair damage.
- Optimum pKa value to inhibit the dental plaque formation around 6.3 and this value comes in the range of chitosan pKa value (5.1-6.5)
- Chitosan has an ability to bind with enamel to create a protective layer that cause reduction of dental abrasion
- Chitosan has been exploited especially as an excipient in pharmaceutical formulation. Due to its hydrophilic nature it can be used as disintegrating and binder agent for tablet dosage form
- Gel forming capability of chitosan based polymeric matrix helps in control and sustained drug delivery
- Positively charged chitosan easily bind with free fatty acid and block the absorption of lipid in the gut. Chitosan also emulsify the fat and disrupts the lipid absorption in the intestine
- High molecular weight of chitosan and presence of amino and hydroxy group makes it suitable for pharmaceutical excipient as thickening agent , surfactant, emulsifier etc.
Our Advantages
Product Quality Advantages
Vast Production Capacity With an annual production capacity of 5,000 tons, we guarantee a long-term and stable supply to meet your needs.
Innovative Separation Technology Our research and development team, consisting of 28 highly skilled professionals, pioneers in separation technology, ensures our leading edge in product innovation and development.
Unmatched Product Purity for Fatty alcohol polyoxyethylene ether The product purity of Fatty alcohol polyoxyethylene ether has reached an industry-leading level of over 99%, a significant achievement that not only redefines market standards but also showcases our commitment and pursuit of product quality. This exceptional purity guarantees efficient performance and stability of Fatty alcohol polyoxyethylene ether across various applications, meeting or even exceeding the most stringent specifications.
FAQ
1. Can I get samples?
Yes, free samples are available.
Samples will usually be sent out within 1-3 working days.
2. Do you accept customized orders?
Yes, both product and package can be customized.
3. What is the payment terms?
TT, LC, DP are available.
Please note that OME orders require payment prior to shipment.
4. What is the lead time for mass production?
Delivery time depends on product type and quantity.
Our company has a digital ordering system to ensure scientific and reasonable scheduling of orders, please consult the sales staff you contacted.
5. How to guarantee the product quality?
We have a complete raw material inspection, quality control and pre-factory inspection system to ensure that the order delivered to you is in line with the contract.
In addition, it also supports third-party inspection before shipment. If the inspection fails, the customer's payment will be refunded, and the loss caused by the breach of contract will be compensated.
6. How to check the order status after payment?
After the order is confirmed, the merchandiser will follow up every week and update the order status to you by email.
7. How to deal with after-sales problems?
The after-sales service implements the order responsibility system, and the salesman is the first responsible person for the order. The after-sales service department will set up a service team after receiving the complaint. They will complete the incident investigation and provide you with a resolution within 72 hours.
Why Choose Us
Over Two Decades of Expertise Leverage our extensive 22+ years of experience to guide every phase of your order, ensuring a seamless and worry-free process.
Comprehensive Order Supervision From the moment you reach out to us, every step of your order is meticulously supervised to alleviate any concerns you might have.
--Engage with our dedicated sales team for swift responses within 12 hours.
--Gain clarity on quality, price, payment terms, packaging, and delivery timelines to facilitate your decision-making.
--Shipping information is promptly shared on the departure day.
--Stay informed at each stage until the successful receipt of your shipment.
Expert Loading Report Services An external team meticulously inspects loading operations to ensure everything is in perfect order, backed by a detailed Loading Report for each shipment, with prior samples available upon request.
Unbeatable Pricing Our profound industry insight, coupled with strong partnerships with select manufacturers, enables us to offer the most competitive prices.
Quality Assured Products We only approve products that meet the highest international standards and regulations.
Strategic Warehouse Solutions With our warehouse services, we ensure a stable supply for our clients, buffering against the volatility of material prices.
Company Profile
Sincere Chemical Co., Ltd., established in 2021, is located in the Huarun Mansion, Longhua District, Haikou City, Hainan Province, boasting a brand-new, ultra 5A-level office environment. Based on the profound corporate culture of Shijiazhuang Chenghexin Chemical, which has more than 20 years of experience, the company fully supports the development of import and export-related businesses for its Hainan branch. The company has a harmonious atmosphere, generous benefits, and offers substantial room for growth.
Since its inception, the company has always adhered to the development philosophy of "integrity, stability, innovation, and precision". It continuously explores and innovates, enhancing the R&D and production capabilities of new products. The company's products are constantly optimized and perfected, and it maintains long-term stable cooperation with domestically powerful factories as well as national and provincial scientific research institutes. This ensures that the products' technology is advanced, quality is stable, and prices are competitive, now forming a professional chemical raw material supply enterprise that combines science, industry, and trade with both domestic and international trade.
In recent years, the company has won several national and provincial awards and titles for being a trustworthy enterprise and has been recognized as a quality and efficiency-oriented enterprise. It has also received accolades and recommendations from internet companies like, Baidu, and HC.com; particularly, it has been featured in a special interview and promotion by the CCTV Securities Information Channel's "Brand Power" program.
After more than 20 years of efforts, the company has continued to grow and expand. Its client base includes highly influential local enterprises, listed companies, and Fortune 500 companies, earning long-term trust and support from both new and old customers. With a bright future ahead, all employees are confident in the company's development.
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